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Mammographic density changes during neoadjuvant breast cancer treatment: NeoDense, a prospective study in Sweden
Skarping, Fornvik, Heide-Jørgensen, Sartor, Hall, Zackrisson, Borgquist
“The majority of patients decreased their MD during [neoadjuvant chemotherapy (NACT)]. We found no evidence of MD as a predictive marker of pCR in the neoadjuvant setting.”
Volumetric breast density is essential for predicting cosmetic outcome at the late stage after breast-conserving surgery
Shiina, Sakakibara, Fujisaki, Iwase, Nagashima, Sangai, Kubota, Akita, Takishima, Miyazaki
“To improve the long-term quality of life after [breast-conserving therapy (BCT)] of breast cancer patients, the correlation of volumetric breast density (VBD) and cosmetic outcome at the late stage after BCT was evaluated … A combination of VBD and PBVE could predict cosmetic outcome after BCT and contribute to the selection for the appropriate BCT.”
Implant volume estimation in direct-to-implant breast reconstruction after nipple-sparing mastectomy
Shia, Yang, Wu, Lai, Huang, Chen
“These implant volume estimate formulas benefit surgeons by providing a preoperative implant volume assessment in DTI reconstruction using the breast volume and an intraoperative assessment using the specimen weight.”
A new method to optimize resection area using a radiation treatment planning system and deformable image registration for breast conserving surgery after neoadjuvant chemotherapy
Miyoshi, Yamaguchi, Fujimoto, Yoshioka, Shiobara, Wakatsuki, Suda, Miyazawa, Aida, Watanabe, Otsuka
“We devised a breast-conserving surgery (BCS) utilizing a new image-processing and projection technique using a radiation treatment planning system (RTPS) and deformable image registration (DIR) for patients with breast cancer after neoadjuvant chemotherapy (NAC).”
Effect of neoadjuvant chemotherapy on breast tissue composition: a longitudinal mammographic study with automated volumetric measurement
Jang, Kim, Chae, Lee, Kim, Lee, Kim
“NAC affects breast tissue composition, reflected as reductions in BV, FGV, and BD. Mammography with automated volumetric measurement can capture quantitative changes in these breast tissue parameters during NAC.”
Longitudinal changes in volumetric breast density with tamoxifen and aromatase inhibitors
Engmann, Scott, Jensen, Ma, Brandt, Mahmoudzadeh, Malkov, Whaley, Hruska, Wu, Winham, Miglioretti, Norman, Heine, Shepherd, Pankratz, Vachon, Kerlikowske
“Automated software can detect volumetric breast density changes among women
on tamoxifen and AI … If declines in volumetric density predict breast cancer outcomes, these measures may be used as interim prognostic indicators.”
Does Mammographic Density have an Impact on the Margin Re-excision Rate After Breast-Conserving Surgery?
Edwards, Guidry, Larson, Novicoff, Harvey, Schroen
“Mammographic density was determined both by breast imaging-reporting and data system (BI-RADS) classification and by an automated software program (Volpara Solutions) … Mammographic density is not associated with an increased need for re-excision or resection of unnecessary margins at initial BCS.”
